The Canes jumped out to a 25-9 lead after a quarter of play and cruised.
Cartersville used a 16-5 run in the second frame to take a commanding 41-14 lead.
Head coach Mike Tobin said the Colts were overmatched and the Canes used reserves liberally after their quick start.
“Our starters played less than half the game,” he said.
Cartersville scored 18 points in the third quarter while allowing seven points. Coahulla Creek closed the game with a 14-12 run in the final period of play.
Corey Tobin led the Canes in scoring with 15 points. Bryce Gober dropped in 11 points and AJ Mosby sank 12.
Cartersville improved to 21-2 overall and 13-0 in region play.
The Canes next play Friday night, which is senior night, entertaining North Murray at home with an 8:30 p.m. tipoff.
The Canes, featuring those seniors, are 48-4 the past two years.
Cass 48, Cedartown 35
Cass started slowly but found traction in the third quarter to claim its second region win Wednesday night with a 48-35 victory over Cedartown.
The Colonels carried a 20-17 lead into halftime and surged to a 36-25 lead with a 16-8 run in the third quarter.
Head coach Greg Scott said a trapping half-court zone by the Colonels forced turnovers by the Bulldogs and made the task easier for his team.
“They turned the ball over 25 times throughout the game,” he said.
Among the Cass scorers were Chavez Hendrix, 9; Walter Brown, 9; Justin Reed, 16. Reed pulled down 12 rebounds for the Colonels while Brown grabbed eight.
Cass raised its record to 9-16 overall and 2-6 in its region.
Paulding County 66, Woodland 50
Paulding County had its shooting touch Wednesday night and that helped it even its season series against Woodland, 66-50.
Woodland had defeated the Patriots, 49-48, on Jan. 14, on a last-second shot.
“When we played at our place, they didn’t shoot all that well,” head coach John Howard said. “Tonight it didn’t seem like they could miss.
“It seemed like they hit probably 55 to 60 percent from the floor. It’s hard to beat a team when they shoot that well.”
Woodland stayed close early, though, and trailed just 18-17 after a quarter of play. Paulding used a 22-11 run to pull ahead 40-28 at the break.
The Wildcats inched back in the third quarter with a 12-11 differential to close to 51-40 but could not get it done in the final period as the Patriots outscored them 15-10.
Carrod Watson led the Wildcats with 10 points. Rasean Davis led Paulding with 27. The Wildcats next play today when they host top-ranked Allatoona.
Howard said his team can expect a challenge.
“We’re looking at this as an opportunity and we need to be loose and try to have some fun on the court,” he said.
The Wildcats will then play Monday against Lithia Springs in the region tournament held at New Manchester. Tipoff is at 6 p.m.